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Prof Le Roux, Prof Farooqi and Dr Forsythe raise awareness of the role of the MC4R pathway in the regulation of bodyweight, and how genetic variants within the pathway can lead to hyperphagia and early-onset, severe obesity at ECO 2023. The speakers discuss understanding monogenic and syndromic MC4R pathway diseases, how to recognise symptoms and when to refer for genetic testing, whilst highlighting the importance of MDT care when treating patients living with MC4R pathway diseases
